Health Canada Confirms DNA Plasmid Contamination of COVID Vaccines

By  Michael Nevradakis, Ph.D.

In what one scientist described as an “admission of epic proportions,” Health Canada on Thursday confirmed the presence of DNA contamination in Pfizer COVID-19 vaccines, and also confirmed that Pfizer did not disclose the contamination to the public health authority.

The DNA contamination includes the Simian Virus 40 (SV40) promoter and enhancer Pfizer did not previously disclose and that some experts say is a cancer risk due to potential integration with the human genome.

Health Canada, the country’s public health authority, told The Epoch Times that while Pfizer provided the full DNA sequences of the plasmid in its vaccine at the time of the initial submission, the vaccine maker “did not specifically identify the SV40 sequence.”

“Health Canada expects sponsors to identify any biologically functional DNA sequences within a plasmid (such as an SV40 enhancer) at the time of submission,” it said.

Health Canada’s admission came after two scientists, Kevin McKernan and Phillip J. Buckhaults, Ph.D., discovered the presence of bacterial plasmid DNA in the mRNA COVID-19 vaccines at levels potentially 18-70 times higher than the limits set by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency.

They tested four expired Pfizer and Moderna vaccine vials “thought to only contain mRNA” and found to contain “double-stranded DNA plasmids.”

Health Canada said, “We have concluded that the risk/benefit profile continues to support the use of the Pfizer-BioNTech vaccine,” and that it does rely on manufacturer claims but “conducts an in-depth independent review” to make sure the vaccines meet “our high standards for safety, efficacy and quality.”

Janci Lindsay, Ph.D., director of toxicology and molecular biology for Toxicology Support Services, told The Defender this statement is “silly, not believable and not defendable,” adding that “We should not have to do the research that they should have done.”

“Why are the FDA, CDC [Centers for Disease Control and Prevention] and the mainstream media still silent about this?” asked Steve Kirsch, founder of the Vaccine Safety Research Foundation, adding that “the mainstream medical community is silent as well.”

Viral immunologist Dr. Byram Bridle of the University of Guelph in Canada, commenting on Health Canada’s admission wrote on his Substack, “This is an admission of epic proportions.”

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The contamination “would have been discovered sooner by independent researchers, but people were threatened with arrest if they supplied vials for analysis,” Kirsch said, claiming he faced threats if he “participated in trying to analyze the vials.”

Bridle noted that it’s been “818 total days” since the University of Guelph banned him from accessing his office and laboratory for attempting to conduct similar research, while other researchers “have been the focus of attacks from many so-called ‘misinformation experts,’” even though none “have been able to refute their findings.”

Plasmid DNA contamination ‘an ongoing problem’

Immunologist, biologist and biochemist Jessica Rose, Ph.D., told The Defender, “Residual DNA has been found in the Pfizer and Moderna — and more so Pfizer — products, in older and newer vials, including the adult monovalent XBB.1.5 [vaccine].”

Rose said this indicates such contamination “is an ongoing problem.”

In separate remarks made Wednesday on CHD.TV’s “Good Morning CHD,” Rose said that McKernan “even looked at the Janssen [Johnson & Johnson vaccine] and discovered residual DNA at very high levels.”

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“Plasmid DNA is used in the manufacturing of mRNA vaccines and is supposed to be removed to a level below a threshold set by health regulatory agencies before the final product is released for distribution,” The Epoch Times reported.

McKernan’s discovery made it “possible for Health Canada to confirm the presence of the enhancer based on the plasmid DNA sequence submitted by Pfizer against the published SV40 enhancer sequence,” Health Canada said.

Health Canada’s revelation came on the same day a new preprint study by Kernan, Rose and others provided more evidence of COVID-19 vaccine contamination in vials from Ontario, Canada.

The paper also presented evidence that Pfizer vaccines used during clinical trials differed from those made available to and administered to the public.

SV40 can ‘potentially integrate into the human genome’ — ‘forever’

SV40 is frequently used in gene therapy for its unique ability to deliver genes to targeted cells.

In the vaccine manufacturing process, SV40 “is used as an enhancer to drive gene transcription,” The Epoch Times wrote. McKernan last month “warned that the presence of DNA plasmids in the vaccines mean[s] they could potentially integrate into the human genome.”

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Christof Plothe, D.O., a member of the World Council for Health’s steering committee, told The Defender the presence of SV40 is “problematic in terms of unwanted immunological reactions and potential integration into the genome, with resulting DNA damage and alteration ability, which can lead to cancer” and “many side effects.”

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Patrick Provost, Ph.D., professor of microbiology and immunology at Laval University in Canada, told The Epoch Times “All it takes is a single integration [of SV40] at the wrong place in a single cell to initiate a cancerous process and kill a person.”

SV40: ‘all risk, no reward’

McKernan told The Epoch Times that because Pfizer’s vaccines already contain the same type of promoter as the one used in Moderna’s vaccine, the inclusion of the SV40 promoter was “completely redundant” and “all risk, no reward.”

Lindsay confirmed this in remarks shared with The Defender, adding that the DNA plasmids are nevertheless harmful even without SV40 present.

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Contamination can lead to cancer, anaphylaxis and other severe reactions

According to Bridle, some potential problems involving DNA contamination include that it can be very long-lasting, has the potential to be incorporated into a person’s chromosomes and can cause inflammation.

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This may have contributed to the high rate of adverse reactions, Rose said. “This is an endotoxin. … if you inject endotoxin into a person as part of a product, you can kill them. What usually happens is they get anaphylaxis. One of the adverse events that we’ve heard a lot of reporting on is anaphylaxis,” a severe allergic reaction, she said.

“Endotoxin injection would induce anaphylaxis and/or sepsis, and there are tens of thousands of reports of these adverse events in VAERS [Vaccine Adverse Event Reporting System] … not considering underreporting,” Rose added, saying “This could also be why we’re seeing a lot of cancer,” though direct evidence of this is still lacking.

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Lindsay took issue with this statement, telling The Defender that “several oncologists have come out to speak on this,” noting that “we have seen an increase in the ICD codes that code for cancers” and adding that “there are all kinds of reports of fast-acting cancers taking people out within days to months of diagnosis.”

Preprint study highlights undisclosed manufacturing change for public vaccines

The findings confirmed by Health Canada were further borne out in the preprint study where Rose, McKernan and several other scientists address the two different processes used to produce Pfizer’s clinical trial vaccine and the version later distributed to the public.

“Production of modRNA used in the original Pfizer randomized clinical trial … utilized a PCR-generated DNA template (Process 1). To generate billions of vaccine doses, this DNA was cloned into a bacterial plasmid vector for amplification in Escherichia coli before linearization (Process 2),” the study notes.

As a result, this expanded “the size and complexity of potential residual DNA” in Process 2 — the vaccines administered to the public — and introduced “sequences not present in the Process 1 template.”

“These data demonstrate the presence of billions to hundreds of billions of DNA molecules per dose in these vaccines,” the study further states, noting that the levels of DNA contaminants exceed thresholds set by the FDA and World Health Organization.

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Text revealing Pfizer’s two different “processes” was buried on page 360 of a 1,413-page document, marked “confidential” and dated Oct. 29, 2020, amending the research protocol for the company’s then-candidate COVID-19 vaccines. It was made public in 2022 as part of the court-ordered release of the “Pfizer documents.”

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According to Bridle, the results of the preprint “are profound,” noting that it “generated the largest data set to date on this topic, using vials from multiple Canadian batches of both the Pfizer and Moderna shots,” finding that all were “contaminated with bacterial DNA” and confirming the presence of SV40 in all Pfizer vials tested.

Rose said, “DNA was found in all 27 Pfizer and Moderna vials” tested and that, as part of the study, the researchers involved “were able to commence a dose response curve using serious adverse event reports for the specific vials tested,” using VAERS data.

According to the study, “A positive dose response relationship was observed for the Pfizer lots based on qPCR estimation of residual DNA,” although Rose told The Defender, “We need more data points, which means we need more vials tested.”

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Via https://childrenshealthdefense.org/defender/canada-dna-contamination-pfizer-covid-vaccine/